Z Phytotherapie 2000;21:127-134. Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Supplements marketed for body-building (ex.. This item: Terry Naturally Traumaplant Comfrey Cream - 1.76 oz (50 g) - Non-Staining Topical Botanical, Free of Toxic Pyrrolizidine Alkaloids (PAs) & Parabens - for External Use Only $20.76 ($11.80/Ounce) Dr. Christopher's Comfrey Ointment, 2 Ounce $11.99 ($6.00/Ounce) Dr Christopher's Formula Complete Tissue and Bone Ointment, 4 Ounce comfrey: [noun] any of a genus (Symphytum) of perennial herbs of the borage family with coarse hairy entire leaves and flowers in one-sided racemes. Comfrey oil shouldnt be used for cooking, like other types of cooking oil. Complementary Health Approaches for Chronic Pain: What the Science Says. 7-6-2001; Lin, C. C., Yang, C. C., Phua, D. H., Deng, J. F., and Lu, L. H. An outbreak of foxglove leaf poisoning. Comfrey is not recommended for internal use because of the liver damage caused by its pyrrolizidine alkaloids. The comfrey plant, Symphytum officinale, gets its name from the Latin confervere, meaning to grow together. To make this recipe, first, you must prepare the comfrey root tincture. Ministry of Environment & Forests, Govt. Follow all directions on the product label and package. The recipe makes about 5 cups of whipped creamy lotion. Dietary Supplements: What You Need to Know. The Comfrey Controversy: Can and Should One Use Comfrey Internally? It has bell-shaped red-violet or yellowish flowers. Do not use this product without medical advice if you are pregnant. View abstract. Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. As we are constantly reviewing and developing our products to meet our consumer needs, consumers, particularly those that suffer from allergies and intolerances, should always check product labelling, warnings, and directions provided with the product that is delivered, prior to use or consumption. All rights reserved. View abstract. It produces clusters of purple, blue, and white flowers, and it's famous for its long . hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. However, it did not affect markers of inflammation or cartilage breakdown over 12 weeks of treatment. Symphytum officinale L, S. asperum Lepechin, S. tuberosum L, Symphytum x uplandicum Nyman. 95 ($14.78/Fl Oz) FREE delivery Wed, Mar 8 on $25 of items shipped by Amazon. The use of babosa (Aloe vera) in treating burns: a literature review. (2018). hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. 2012;101(4):211-216. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications. Efficacy and tolerance of a comfrey root extract (Extr. We comply with the HONcode standard for trustworthy health information. All rights reserved. Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). 12 drops black pepper (Piper nigrum) essential oil All Technology Jobs. The first European settlers of America considered comfrey so indispensable, they carried it on their journey across the Atlantic in the 1600s.2. View abstract. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. (2018). Double boiler Three clinical studies have provided evidence that ointments containing comfrey root have helped reduce back pain. Some of these components are thought to speed up wound healing by stimulating new cell growth. 2013;163:5864 (2013) doi:10.1007/s10354-012-0162-4, Giannetti BM, Staiger C, Bulitta M, Predel HG. The herbal topical cream was prepared at two different strengths, as an additional measure of efficacy. Wien Med Wochenschr. Centurian, South Africa: Medpharm Scientific Publishers. , meaning to grow together. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Symphytum species: A comprehensive review on chemical composition, food applications and phytopharmacology. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Sometimes, massaging on topical ointments can help reduce pain and inflammation. However, further well-designed studies are needed. Ingesting cooking oil has been banned by the European Union, due to a high risk of liver toxicity.9, Adults with liver disease, cancer, or a history of alcoholism are also advised to avoid comfrey because the skin can also absorb the liver-damaging compounds. Do not use extra comfrey to make up the missed dose. 2005 - 2023 WebMD LLC. Make sure to always buy comfrey (Symphytum officianale) root and leaf from a trusted source. We cover all you need to know in this article. Complement Ther Clin Pract. Links to external sites are for informational purposes only. comfrey cream holland and barrett. 2004;154(21-22):498-507. Dosage: How Much Comfrey Cream Should I Use? 4-4-2009;139(13-14):210-211. 2758955. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Recent studies have suggested topical benefits, but more research is needed. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. Comfrey contains chemicals that can cause liver damage, lung problems, or cancer. Understand comfreys contraindications before using it. The efficacy and safety of comfrey. Join rewards for life today and we'll give you 300 points worth 3.00. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis. We comply with the HONcode standard for trustworthy health information. July 6, 2001. NIH Office of Dietary Supplements. 1 Since at least the 4 th century, people have used comfrey medicinally. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Liver injury from herbal and dietary supplements. Ther Drug Monit 2001;23:698-708. Modern science suggests that the ancients were correct in believing comfrey helps to heal woundsand relieve pain.3,4 In this article, well explain where comfrey comes from, comfrey oils remarkable health benefits and how to use it at home. We answer questions, including what are essential oils? & what can I use them for? in this article. Consult your healthcare provider before using. To make this recipe, first, you must prepare the comfrey root tincture. Comfrey is a perennial herb found in moist grasslands in western Asia as well as in North America. An Evidence-Based Reference. Which part of the comfrey plant has the lowest level of pyrrolizidine alkaloids (PAs)? View abstract. Discontinue use if a rash develops. Whether youve been hiking, biking, playing, or enjoying water sports, comfrey cream can be a wonderful ally in supporting achy muscles that result from physical, summertime activities. Jurcu, R., & Jurcu, I. Staiger, C. Comfrey: a clinical overview. After the tincture is made, then you can whip up the fabulous joint and muscle cream! Need some help with an order or want to speak to a member of our Customer Services team? In a randomized multicenter study with 164 ankle sprain patients, swelling and pain were improved more successfully using a comfrey root extract compared to a diclofenac gel (Predel et al., 2005). Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Wang YP, Yan J, Fu PP, Chou MW. Add comfy to Vaseline . Using a supplement like comfrey may have potential side effects. This site uses cookies to improve your experience. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. Therapeutic Research Faculty 2020. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). The combination of Vitamin E, Wheat Germ oil and Rice Bran oil makes this cream perfect for your daily hydration needs. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). Comfrey [Online article]. Shop buy 1 get 1 half price on all gut health products, Buy 1 get 1 Half Price | Plus an extra 20% off 25, App Exclusive | Get an extra 22% off 25 when you spend on the H&B App, Royal Mail strikes may cause a delay to our click and collect service, Looking for fitness advice & inspiration this New Year? Koll, R., Buhr, M., Dieter, R., Petrowicz, O., Gianetti, B., and Wagener, S. Wirksamkeit und Vertraglichkeit von Beinwellextrakt (Extr. Pharmazie 1995;50:83-98. International Journal of Pediatrics and Adolescent Medicine, (4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002. Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. You can purchase the Comfrey Ointment at Boots, Tesco, Sainsbury's or Holland & Barrett. Pyrrolizidine poisoning. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Available for Android and iOS devices. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). of India and by a State Level Environment Impact Assessment Authority constituted by Government of India on the recommendations made . Vithayathil MK, Edwards M. Comfrey herbal remedy causing second-degree heart block: do not be outfoxed by digitalis. Facebook; Twitter; Pinterest; Related Posts. Electric bowl mixer (like a KitchenAid) or a blender, Small glass jars with lids for sharing (optional). . Medically reviewed by Drugs.com on Feb 8, 2023. Natural Standard. Avoid taking comfrey orally (by mouth). We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. Comfrey is an herb in the Boraginaceae family and has small purple flowers. It should never be taken by mouth. Comfrey contains chemicals that cause serious liver damage when taken by mouth. It's typically only used in small amounts for a very short period. Comfrey root: from tradition to modern clinical trials, Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial, Topical herbal therapies for treating osteoarthritis, Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials, Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. Close LOGIN FOR DONATION. It is called knitbone or boneset, referring to the bone-like growth of its roots. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Wien.Med.Wochenschr. In a randomized, double-blind, placebo-controlled trial, 220 patients with knee osteoarthritis used either a commercial topical comfrey root extract or a placebo. OTHER NAME(S): Ass Ear, Black Root, Blackwort, Bruisewort, Common. Other drugs may interact with comfrey, including prescription and over-the-counter medicines, vitamins, and herbal products. Label with the ingredients and date made. View abstract. This site uses cookies to improve your experience. New South Wales Health, Australia. Barthomeuf, C. M., Debiton, E., Barbakadze, V. V., and Kemertelidze, E. P. Evaluation of the dietetic and therapeutic potential of a high molecular weight hydroxycinnamate-derived polymer from Symphytum asperum Lepech. Also, avoid use for more than two weeks or excessive concentrations containing more than 100 mcg of pyrrolizidine alkaloids (Wichtl, 2004 & Ulbricht, 2010). Medicine makers would bind comfrey leaves and roots in poultices, then apply those poultices to the skin to treat injuries. Wound-healing effects of a symphytum herb extract cream (Symphytum uplandicum Nyman) in children: A randomized double-blind study. View abstract. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. Herbal drugs and phytopharmaceuticals. Symphytum officinale L., dermal use (Flexagile cream)]. Registered VAT no. Select a condition to view a list of vitamins. After 7 years in this role and a further year working as a drug safety officer in the pharmaceutical industry, Bhupesh joined Holland &Barrett as a Senior Regulatory Affairs Associate in 2019. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. It may contain small amounts of toxic pyrrolizidine alkaloids. Phytother.Res 2012;26(10):1441-1448. Further study is needed to confirm these results. This recipe is contraindicated for small children and those with certain medical conditions. We are building the future of Health and Wellness Tech. Other prescription medicines that may harm the liver include: Some supplements may also harm the liver, including: It is essential to carefully read a supplement's ingredient list and nutrition facts panel to know which ingredients and how much of each ingredient is included. WebMD does not provide medical advice, diagnosis or treatment. Do not use different forms (tablets, liquid, tincture, teas, etc) of comfrey at the same time without medical advice. Learn more in. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. Frost R, Macpherson H, O'meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). For this reason, some topical products are advertised as made from comfrey leaves, but it's safest to choose a PA-free product. Squish and squeeze as many leaves into as you can into the container. Braz J Biol. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. View abstract. Drugs and Lactation Database (LactMed). It is easily absorbed to leave your skin feeling fresh, soft and radiant. Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. One study followed 142 patients with ankle sprains. We're proud to make a difference, and you can to. My family has used comfy for ingrown toenails. Rad. A large review released in 2013 about the medicinal uses of comfrey stated: It is clinically proven to relieve pain, inflammation and swelling of muscles and joints in the case of degenerative arthritis, acute myalgia in the back, sprains, contusions and strains after . Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. #HBTechCareers. No comments. Experts suggest not using comfrey cream for longer than ten days in a row. Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. (10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). CLICK HERE TO ENTER! If your healthcare provider recommends it, make sure to use it on intact skin for a small amount of time, and be careful that infants do not ingest it. 2004;11(6):470-477. 1/8 cup comfrey tincture (Symphytum officinale), store bought or via recipe, above. View abstract. This article discusses the uses and benefits of comfrey cream. Thus, it is not advised to ingest herbal preparations of comfrey unless guided by an expert pharmacologist and physician. Am J Med 1990;89:547-8. Using different formulations together increases the risk of an overdose. Yield: Approximately 5 cups of whipped lotion. Set on a sunny windowsill and shake once a day for 2-4 weeks. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. Comfrey [Online article]. If you're considering using the cream, consult your healthcare provider first. Comfrey is changed and broken down by the liver. Fortschr Med Orig 2002;120:1-9. View abstract. Be sure to choose organic carrier oils and essential oils when possible. Contact your doctor or pharmacist if you have any questions before use. 2013;163(3-4):58-64. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: Results of a double-blind, randomised, placebo controlled, multicentre trial. To reduce the risk of side effects, never apply comfrey cream to broken skin or open wounds as it may be more highly absorbed by the body. Mackinnon, M. In general practice, 'always expect the unexpected'. Registered VAT no. The FDA has recommended that all comfrey products that are taken by mouth be removed from the market. View abstract. 1 It's found in Europe, Asia, and North America. By Megan Nunn, PharmD A review of 26 clinical trials concluded that mild skin reactions were the most common side effects of comfrey creams used in the studies. Symphyti) bei Sprunggelenks-distorsionen. Comfrey is often sold as an herbal supplement. Metabolism, genotoxicity, and carcinogenicity of comfrey. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. A handbook for practice on a scientific basis. Turn off heat and give it a good stir. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. View abstract. First, make the comfrey root tincture by combining the dried comfrey root and alcohol in a sterilized, dry, glass pint jar. A multi-center, randomized, double-blind, controlled clinical trial was conducted with 161 patients having acute lower back pain. When considering the use of herbal supplements, seek the advice of your doctor. Find out how to use it here along with its benefits. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Knee pain and stiffness can be a stubborn concern that keeps many from doing activities they enjoy. Allow the oil mixture to cool until it reaches room temperature, which could take 8-12 hours. Comfrey is likley unsafe to take by mouth. Penetration of lycopsamine from a comfrey ointment through human epidermis. Osteoarthritis Cartilage. What are the benefits of using it? In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. https://doi.org/10.1007/s10354-007-0474-y. As a Licensed Massage Therapist, I have personally made this comfrey cream recipe multiple times and given jars to my clients. Staiger, C. Comfrey root: from tradition to modern clinical trials. Comfrey's original name, knitbone, derives from the external use of poultices of its leaves and roots to heal burns, sprains, swelling, and bruises. Learn more in The Comfrey Controversy: Can and Should One Use Comfrey Internally? Comfrey is considered likely unsafe to use if you are nursing a baby. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Vickers AJ, Vertosick EA, Lewith G, et al. In another study, participants with ankle sprains received either comfrey root extract cream or diclofenac gel, a nonsteroidal anti-inflammatory drug (NSAID). The Effect of Comfrey on Enoxaparin-Induced Bruise in Patients with Acute Coronary Syndrome: A Randomised Clinical Trial. D'Anchise, R., Bulitta, M., and Giannetti, B. Comfrey extract ointment in comparison to diclofenac gel in the treatment of acute unilateral ankle sprains (distortions). This comfrey cream recipe works great for local areas that have mild bruising or soft tissue pain. Topical comfrey is for use only on the skin. Eucalyptus oil is used externally to stimulate blood flow. View abstract. DOI:10.1211/PJ.2021.1.69803. Comfrey cream View abstract. Regarding its antioxidant, antilipoperoxidant, antiinflammatory, and cytotoxic properties. Hybrids and other species may have a similar appearance but could have significantly different amounts of the toxic pyrrolizidine alkaloids (Kucera et al., 2018). Comfrey root extracts have been used by herbalists and in folk traditions for centuries to soothe aches and pains. Choose organically grown comfrey when possible. A later study of 133 peoplefound some evidence that a topical combination of comfrey extract and tannic acid led to reduced knee pain.
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